Together, we are changing the world. With the close of Break Through: The Caltech Campaign, we thank our friends and supporters for empowering Caltech scientists and engineers to push the boundaries of science and technology toward a brighter future for us all.

Every breakthrough opens new paths forward.

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Driven by curiosity. Funded by people. Selected Campaign Breakthroughs

How can the smallest things help us tackle the biggest problems?

Supported in part by the Resnick Sustainability Institute, Dianne Newman, the Gordon M. Binder/Amgen Professor of Biology and Geobiology, and her team are investigating how microorganisms co-evolve with their environments. Insights into the makeup of microbiomes could inform applications ranging from better treatments for chronic infections to greater crop yields to feed the planet’s growing population.

Discover how

When do decisions become habits?

Colin Camerer, director and leadership chair of the T&C Chen Center for Social and Decision Neuroscience and the Robert Kirby Professor of Behavioral Economics, studies how habits form and when decisions shift from being active choices to automatic routines. During the pandemic, he and his team decided to zero in on the lasting ripple effects of hand washing and other behavioral changes sparked by COVID-19.

Figure it out

How does the gut influence the brain?

Sarkis Mazmanian, the Luis B. and Nelly Soux Professor of Microbiology, has discovered links between gut bacteria and the health of our immune and nervous systems. Now, because the gastrointestinal tract is easier to access pharmaceutically than the brain, he aims to develop ways to treat autism, Alzheimer’s disease, and other neurological disorders by way of the gut.

Learn how